2025 AB Nexus Grant Awards

Optimizing Beneficial Fungi to Support Infant Gut Health and Prevent Infection

ÌýÌýCU Anschutz PI: (Microbiology)
ÌýÌýCU Boulder PI: Jennifer Hill (Molecular, Cellular & Developmental Biology)
​ÌýÌýExploratory track ($75K)

This research explores how certain Candida fungi in the gut can either help or harm babies during early development. By studying two closely related fungal species—one that supports healthy growth and one that can cause infections—the team hopes to understand what makes some microbes beneficial and others dangerous, with the goal of promoting health and avoiding disease.

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Studying How Baby Diets Shape Their Microbiomes—and Future Allergy Risk

ÌýÌýCU Anschutz PI: (Pediatrics)
ÌýÌýCU Boulder PI: Matthew Olm (Integrative Physiology)
​ÌýÌýExploratory track ($75K)

This study investigates how different infant diets—vegetarian versus meat-based—shape gut microbes and influence immune cells linked to allergies. By analyzing the impact of different infant fecal samples in animal models, researchers aim to uncover how early-life microbiomes impact inflammation, laying the groundwork for future dietary or probiotic strategies to prevent conditions like food allergies and asthma.

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Harnessing AI-Quantum Computing for Colorectal Cancer Therapies

ÌýÌýCU Anschutz PI: (Pharmaceutical Sciences)
ÌýÌýCU Boulder PI: Karolin Luger (Biochemistry)
​ÌýÌýQuantum and Human Health track

This project uses cutting-edge quantum computing technologies, AI and the resources of the CU Anschutz Center for Drug ÁñÁ«ÊÓÆµ18y to accelerate new treatments for colorectal cancer. By optimizing a promising class of drugs that target a key protein involved in tumor progression, the team aims to improve chemotherapy effectiveness and bring a new therapy closer to clinical trials—all while positioning Colorado as a leader in quantum-powered health innovation.

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Using Quantum Sensing to Detect Pneumonia and Asthma in Children

ÌýÌýCU Anschutz PI: (Pediatrics)
ÌýÌýCU Boulder PI: Jun Ye (Physics)
​ÌýÌýQuantum and Human Health track

Using quantum sensing and advanced laser technologies, this project aims to develop a new breath test to help doctors quickly and safely differentiate between bacterial pneumonia, viral infections and asthma in children. By analyzing a child’s breath molecules, the team hopes to improve the process of diagnosis, reduce unnecessary treatments, and create a portable tool for use in hospitals and clinics.

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